What type of sample is critical for molecular diagnostics?

Molecular diagnostics primarily focus on the detection and analysis of nucleic acids, such as DNA and RNA, to identify genetic disorders, infectious diseases, and various conditions at the molecular level. These tests require high-quality nucleic acid samples because they are designed to amplify and analyze specific sequences to identify genetic material, pathogens, or biomarkers.

If the sample does not contain nucleic acids or is degraded, the accuracy and reliability of the tests performed will be compromised. Therefore, the correct type of sample necessary for molecular diagnostics is indeed nucleic acid samples, as they are essential for the methodologies used in this field, such as PCR (Polymerase Chain Reaction) and sequencing techniques.

Other sample types, while useful in certain diagnostic contexts, do not provide the critical nucleic acid component required for molecular analysis and thereby lack the specificity necessary for molecular diagnostics.